Predict and Explain Human Toxicity Before Clinical Failure.

Move beyond the limitations of animal models and legacy assays. DeepCyte's AI-powered Single-Cell Metabolomics identifies drug toxicity with 94% accuracy, providing actionable mechanistic insights at sublethal concentrations.


In today's high-stakes pharmaceutical landscape, 9 out of 10 drugs fail to reach the market. The primary "silent saboteur" is toxicity, which accounts for 30% of all program terminations. These failures represent a staggering $2.6 billion gamble that typically ends in a "no" because existing tools provide data that is too shallow, too late, and lacks mechanistic explanation.

DeepCyte is bridging this resolution gap. Our proprietary single-cell metabolomics technology — refined through 10+ years of R&D — offers 1,000× the information content of conventional molecular methods. Complementing and outperforming legacy assays and other predictive tools, DeepCyte builds AI to predict and explain exactly how a drug causes toxicity at the cellular level.

Why DeepCyte Is the Strategic Choice

Mechanistic Clarity

We provide the "why" behind every prediction, identifying toxicity mechanisms following the Adverse Outcome Pathways framework.

Early De-risking

Detect molecular shifts at sublethal concentrations, allowing you to identify and deconvolve co-existing toxicity types triggered by the same compound long before they manifest as cytotoxicity or clinical features.


Request the Technical Demo today to see how DeepCyte identifies concurrent toxicity mechanisms at sublethal concentrations.

See the Future of Your Compound

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The Problem

Challenge We Address

Drug development faces a crisis. Despite billions invested, most compounds fail — and toxicity is the silent killer.

88%

of drugs entering clinical trials never reach patients

30%

of failures are linked to safety concerns discovered too late

$780M+

in R&D funding lost per program due to toxicity failures


Our solution

DeeTox, Single-Cell advantages of the technology.

Explainable Predictive Toxicology

Our AI reveals the biological "why" behind every toxicity prediction — delivering mechanistic insight, not just a risk score.

Metabolic Network Mapping

Our AI detects shifts in metabolic markers and connects predictions to their biological causes.

Sublethal Detection

Identify toxicity at concentrations before they become lethal, catching problems earlier in development.


The Technology Behind the Breakthrough

Two revolutionary platforms working in concert to transform drug safety prediction

MetaCore™

The Foundation

High-throughput platform processing 100,000+ cells from 100+ samples in under 10h. Best in class in reproducibility, coverage, throughput.

  • Ultra-high throughput single-cell analysis
  • Cost-effective metabolomics profiling
  • Rapid turnaround for decision-making
DeeTox

The Solution

Single-cell mechanistic AI delivering unprecedented insights into toxicity mechanisms.

  • Sublethal Detection Predict AOP toxicity pathways before they become lethal, identifying risks at the earliest possible stage.
  • Deconvolution Separate co-existing AOP toxicity pathways triggered by the same compound for precise understanding.
  • Mechanistic Clarity Reveal the specific molecular rewiring triggered by your drug, enabling rational optimization.

How DeepCyte Compares

See the advantages of AI-powered single-cell metabolomics.

Feature
Animal Testing
High Throughput Screening
QSAR
Cell Painting
DeeTox
FeatureHuman Relevance
Animal TestingLimited (species differences)
High Throughput ScreeningHigh
QSARModel-dependent
Cell PaintingHigh
DeeToxHigh
FeatureSingle-Cell Resolution
Animal TestingNo
High Throughput ScreeningNo
QSARN/A
Cell PaintingYes (emerging)
DeeToxYes (deconvolves cell subpopulations)
FeatureMechanistic “Why”
Animal TestingYes (requires follow-up studies)
High Throughput ScreeningYes (assay-dependent)
QSARYes (structure-based prediction)
Cell PaintingYes (morphological)
DeeToxYes (biochemical)
FeatureMolecular Insights
Animal TestingYes (requires dedicated bioanalysis)
High Throughput ScreeningYes (per target)
QSARPredicted (in silico)
Cell PaintingIndirect (image-derived features)
DeeToxYes (endogenous metabolites)
FeatureLabel-Free Measurements
Animal TestingMixed
High Throughput ScreeningNo
QSARN/A
Cell PaintingNo
DeeToxYes
FeatureSublethal Sensitivity
Animal TestingYes (costly, late-stage)
High Throughput ScreeningAssay-dependent
QSARModel-dependent
Cell PaintingYes (morphological)
DeeToxYes (biochemical)
FeatureThroughput
Animal TestingLow
High Throughput ScreeningVery high
QSARVery high
Cell PaintingHigh
DeeToxModerate
FeatureStage of Use
Animal TestingRegulatory
High Throughput ScreeningEarly discovery / Regulatory
QSAREarly discovery
Cell PaintingEarly discovery / Emerging regulatory
DeeToxEarly discovery
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